Backblaze got a pretty significant performance update today. I currently do my off-site backups to Amazon via Arq, but only for about 20GB worth of data. If you want to back up everything to an off-site location, and don’t want to pay exorbitant monthly fees to S3, I highly recommend Backblaze.
On a related note, I wrote about off-site backups and Backblaze, Crashplan, and Arq a while back.