Michael Agger, writing at Slate about natural scrolling:
Apple had decreed that “natural scrolling” was the new standard, overturning 25 years of convention. This was more discomfiting than rearranging furniture. This was pulling out the chair as you were taking a seat.
I disabled natural scrolling right away when I began using the beta builds of Lion, but once it shipped and the camps were divided (those who had gotten used to it and loved it, and those who couldn’t handle it) I gave it a second chance. It took me about 10 days to get used to it but now that’s ancient history.